Essential Athrombia

Seref Inceman; Asuman Ünügür; Metin Aran

doi:10.1055/s-0038-1655446

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1962; 08(03): 502-510
DOI: 10.1055/s-0038-1655446

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

Essential Athrombia

Authors

Seref Inceman

¹Third Internal Clinic of Istanbul University, Guraba Hospital, Istanbul, Turkey
Asuman Ünügür

¹Third Internal Clinic of Istanbul University, Guraba Hospital, Istanbul, Turkey
Metin Aran^*

¹Third Internal Clinic of Istanbul University, Guraba Hospital, Istanbul, Turkey

Abstract

PDF Download

Summary

A severe hemorrhagic disease was observed in a 15 month old infant. The laboratory studies revealed only one anomaly in the hemostatic mechanism of the patient: an impairment of the functions of agglomeration and adhesivity of his platelets. The authors believe that this is the second case in literature. The agglomeration and adhesive faculty of blood platelets and the relation of these platelet functions with blood coagulation, clot retraction and viscous metamorphosis are discussed.

PDF (9076 kb)

References

References
1 Alatas S, Ulutin O. N. Etude au microscope électronique des thrombocytes d'un cas de thrombopathie congénitale. New Istanbul Contr. clin. Sci. 1954; 3: 22
2 Alatas S, Gürtürk S. Etude des thrombocytes au microscope électronique dans 2 cas de thrombopénie secondaire survenue au cours de l'infection tuberculeuse. New Istanbul Contr. clin. Sci. 1955; 3: 268
3 Apitz K. über Profibrin: V. Die Agglutination von Blutplättchen durch Profibrin. 2. ges. exp. Med. 1939; 105: 89
4 Biggs R, MacFarlane R. G. Human blood coagulation and its disorders. Second Edition Blackwell Scientific Publications; Oxford: 1957
5 Biggs R, Douglas A. S. The thromboplastin generation test. J. clin. Path. 1953; 6: 23
6 Bizzozero G. über einen neuen Formbestandteil des Blutes und dessen Rolle bei der Thrombose und der Blutgerinnung. Virchows Arch. path. Anat. 1882; 90: 267
7 Bounameaux Y. Etude de l'adhésivité des plaquettes in vitro dans diverses thrombo-pénies. Sang 1955; 26: 872
8 Braunsteiner H, Fellinger K, Pakesch F. Elektronenmikroskopische Untersuchungen der Plättchen bei Thrombasthenien. Klin. Wschr. 1953; 21
9 Braunsteiner H, Fellinger K, Pakesch F. Structural changes in the platelets as observed by electron microscopy. Blood 1954; 9: 595
10 Braunsteiner H. Thrombopathie und Thrombasthenie. Wien. Z. inn. Med. 1955; 36: 421
11 Brinkhous K. M, LeRoy E. C, Cornell W. P, Brown R. C, Hazle-hurst J. L, Vennart G. P. Macroscopic studies of platelet agglutination, nature of thrombocyte agglutinating activity of plasma.. Proc. Soc. exp. Biol. (N. Y.) 1958; 98: 379
12 Cristalli M, Cotellesa G. Contributo alla conoscenza dello malattia di v. Willebrand-Jürgens. Minerva pediat. 1952; 7: 272
13 Eberth J. C, Schimmelbusch C. Experimentelle Untersuchungen über Thrombose. Arch. path. Anat. 1886; 103: 39
14 Feissly R, Lüdin H. Microscopie par contrastes de phases. III. Application à l'hématologie. Rev. Hémat. 1949; 4: 481
15 Frank E. Die hämorrhagischen Diathesen. Schittenhelm: Handb. d. Krankheiten d. Blutes. Springer; Berlin: 1925
16 Frank E, Ulutin O. N, Karaca M. Die isolierten und assoziierten Athrom-bien. New Istanbul Contr. clin. Sc. 1956; 4: 1
17 Frank E. Essential thrombopenia reconsidered after 40 years. New Istanbul Contr. clin. Sci 1956; 4: 53
18 Frank E, Ulutin O. N. A study concerning two cases of vascular hemophilia (Athrombia hemophilica). 7th Intern. Congr. int. Soc. Hematol., 7.–13. Sept. 1958. Rome.:
19 Glanzmann E. Hereditäre hämorrhagische Thrombasthenie. Jb. Kinderheilk. 1918; 88: 113
20 Glanzmann E. Thrombasthenie in der ersten Lebenszeit. Arch. Kinderheilk. 1951; 141: 191
21 Guichard A, Revol L. Les diathèses hémorrhagiques à plaquette rondes et isolées. Sang 1949; 20: 434
22 Hartmann E. über das Wesen der Blutgerinnungsstörung bei schwerer Erkrankung des Leberparenchyms. Klin. Wschr. 1927; 1322.
23 Hayem G. Sur le méchanisme de l'arrêt des hémorragies. R. Acad. Sci. 1882; 95: 18
24 Hellem A. J. The Adhesiveness of Human Blood Platelets in vitro. Monograph. University Press; Oslo: 1960
25 Hirsch E. O, Favre-Gilly J, Dameshek W. Thrombopathie thrombocytopenia; successful transfusion of blood platelets. Blood 1950; 5: 568
26 Inceman S. Thrombopathie hémorragique avec altération élective des fonctions d'agglutination. 5th Internat. Congr. Haemat.; Paris: 1954
27 Inceman S. Thrombopathie hémorragique avec altération élective des fonctions d'agglutination. Sang 1955; 26: 190
28 Inceman S. Agglutinability and adhesivity of platelets. Forum med. (Istanbul) 1956; 2: 105
29 Inceman S. Investigation with contrast phase microscope of the relationship between the agglutination and adhesion of the platelets and the retraction of the coagulum. Forum med. (Istanbul) 1956; 2: 35
30 Inceman S. La valeur clinique de Pagglutinabilité et de l'adhésivite des thrombocytes. Sang 1956; 27: 565
31 Inceman S. Thrombositlerin aglütinasyon ve adezyon fonksiyonlarinin kontrast faz mikroskopu teknigi ile incelenmesi. Thesis, Istanbul 1956
32 Inceman S. Clinical States of Thrombocytic Hypoagglutinability and Hypoadhesi-vity. 6th Intern. Congr. intern. Soc. Hematol. 27. Aug.–1. Sept. 1956. Boston.:
33 Inceman S. Athrombie transitoire. Sang 29: 256 1958;
34 Inceman S, Ulutin O. N, Karaca M. Thrombocytopathie acquise et secondaire. 7th Intern. Congr. int. Soc. Hematol. 7.–13. Sept. Rome 1958
35 Inceman S, Uçar S, Ulutin O. N. Athrombia thrombocytopathica. Thrombos. Diathes. haemorrh. 1960; 4: 234
36 Jensen E, Sauthoff R. Zur Frage der Thrombopathien im Kindesalter. Arch. Kinderheilk. 1949; 136: 65
37 Jürgens R, Naumann W. Klinische und experimentelle Untersuchungen über Funktionen der Blutplättchen. Dtsch. Arch. klin. Med. 1931; 172: 248
38 Jürgens R, Ferlin A. über den sog. Prothrombin -Consumption-Test bei Hämophilie und bei konstitutioneller Thrombopathie (v. Willebrand-Jürgens). Schweiz. med. Wschr. 1950; 41
39 Jürgens R, Forsius H. La thrombopathie essentielle type v. Willebrand-Jürgens aux Iles Aaland. Schweiz. med. Wschr. 1951; 1248.
40 Lenggenhager K. Irrwege der Blutgerinnungsforschung. Klin. Wschr. 1936; 1835
41 Moolten S. E, Vrornan L. The adhesiveness of blood platelets in thromboembolism and hemorrhagic disorders. I. Measurement of platelet adhesiveness by the glass wool filter.. Amer. J. clin. Path. 1949; 19: 701
42 Naegeli O. Blutkrankheiten und Blutdiagnostik. Berlin 1931
43 Osler W. On certain problems in the physiology of blood corpuscles. Med. News (N. Y.) 1886; 48: 356
44 Quatrinn N. Emofilia e trombopatia. Progr. med. (Napoli) 1953; 9: 115
45 Quick A. J, Favre - Gilly J. E. The Prothrombin Consumption Test its clinical and theoretical implications. Blood 1949; 4: 1281
46 Quick A. J. The physiology and pathology of hemostasis. Lea and Febiger; Philadelphia: 1951
47 Quick A. J. Hemorrhagic Diseases. Lea and Febiger; Philadelphia: 1957
48 Reiner E, Vetter H. Un nouveau cas de thrombopathie constitutionelle de v. Willebrand-Jürgens. Klin. Wschr. 1952; 1086
49 Revol L. Diathese hémorragique avec grosses anomalies morphologiques des plaquettes. Sang 1945; 16: 23
50 Revol L. Les thrombocytes pathologiques en contraste de phase. 4th Congr. Europ. Soc. Hematol. Sept. Amsterdam 1953
51 Revol L. A propos de 3 nouveaux cas de "Diacyclo-Thrombopathie". L'épreuve de l'étalement des plaquettes en contraste de phase. Sang 1954; 25: 122
52 Revol L, Mornex Viala. Un nouveau cas de diacyclothrombopathie. Heureuse influence de la cortisone. Sang 1955; 26: 622
53 Sautoff R. Zur Frage der Thrombopathien. ärztl. Wschr. 1951; 637
54 Savitsky J. P, Werraan R. Platelet adhesiveness and clot retraction time. Amer. J. clin. Path. 1952; 22: 1175
55 Savitsky J. P. A plasma factor for platelet adhesiveness and clot retraction acceleration. Blood 1953; 8: 1091
56 Sharp A. A. Platelet (Viscous) Metamorphosis. The Blood Platelets. Int. Symp. Henry Ford Hospital. March 17.–19. 1960, Detroit (Mich.) 1960
57 Shionoya T, Rowntree L. G. Studies in Experimental Extracorporal Thrombus Formation. J. exp. Med. 1927; 46: 7
58 Stefanini M, Silverberg J. H. Studies on platelets: I. The relation of platelet agglutination to the coagulation mechanism.. Amer. J. clin. Path. 1951; 21: 1030
59 Still B. M. Experiments on plasma clot contraction. Blood 1952; 7: 808
60 Sussman L. N, Wald N, Rosenthal R. L. A hemorrhagic diathesis due to a qualitative platelet defect. Blood 1952; 7: 1100
61 Tocantins L. M. Platelets and the structure and physical properties of blood clots. Amer. J. Physiol. 1936; 114: 709
62 Ulutin O. N. The Qualitative Platelet Diseases. The blood platelets. International Symposium, Henry Ford Hospital. March 17.–19. 1960, Detroit (Mich.) 1960
63 Van Creveld S. Recherches Concernant quelques maladies a diathèse hémorragique. Schweiz. med. Wschr. 1952; 399
64 v. Willebrand E. A, Jürgens R. über ein neues vererbbares Blutungsübel: Die konstitutionelle Thrombopathie. Dtsch. Arch. klin. Med. 1933; 175: 453
65 Wolpers C. Cited by Sauthoff.
66 Wright H. P. Adhesiveness of blood platelets in hemophilia. Lancet 1946; 1: 306